This is why we allow the ebook compilations in this website. It breaks down ACh into acetic acid and choline. Tubocurarine causes _______________ via competitive blockade. What is the primary role of the enzyme acetylcholinesterase (AChE) at a cholinergic synapse? Which of the following does NOT describe treppe? What is the primary role of the enzyme acetylcholinesterase (AChE) at a cholinergic synapse? Which of the following can trigger a muscle twitch? Acetylcholinesterase is an enzyme that can be found within the neuromuscular junction. Which of the following is proportional to the amount of tension produced by a skeletal muscle? Acetylcholinesterase exists at parasympathetic and sympathetic __________, at parasympathetic ___________, and at somatic muscle (neuromuscular junction). Acetylcholinesterase inhibitors can be poisonous due to stimulation of ______________ and _____________ receptors, as well as stimulation of ____________. AChE is a glycoprotein that exists is several forms. Which of the following proteins contains the active site involved in cross-bridge formation? Treppe is the phenomenon that results in _______. Learn vocabulary, terms, and more with flashcards, games, and other study tools. Which of the following occurs during the contraction phase? When the frequency of stimulation of a muscle is great enough, _______. Nicotinic receptors can be found at ________________. It looks like your browser needs an update. Inside a muscle, bundles of single muscle fibers form _____. Phase II depolarizing blockade involves ______________. __________ is the main root of acetylcholine degradation from the synaptic cleft. It is an enzyme that catalyzes the breakdown of acetylcholine and of some other choline esters that function as neurotransmitters. Right next to the receptor is acetylcholinesterase, the enzyme which breaks up acetylcholine into acetate and choline. NO force is generated during which of the following? Which of the following is most directly responsible for the coupling of excitation to contraction of skeletal muscle fibers? The involuntary muscles that control movement of the diaphragm is what allows for a person to inhale and exhale, getting the oxygen into their bodies. Acetylcholinesterase. Acetylcholine is released when a nerve impulse reaches a myoneural junction. b. Physostigmine, neostigmine, and pyridostigmine are carbamate ____________. Edrophonium is a non-covalent ______________. Insecticides and nerve gases are ________________ that _____________ acetylcholinesterase. Drugs and substances that interrupt acetylcholine function can have negative effects on the body and can even lead to death. The resting length of the muscle _______. Asked by Wiki User. What mechanism releases neurotransmitter from presynaptic neurons? Where does the acetylcholine that stimulates muscle contraction bind? To transition from unfused tetanus to fused tetanus, _______. Treatment of muscarinic intoxication by acetylcholinesterase inhibitors can include muscarinic antagonists such as _______________, or the acetylcholinesterase reactivator ___________. 1.What is the role of AChE in the NMJ? What is the role of acetylcholine in a skeletal muscle contraction? When the sarcomere is at rest, what is covering the active sites on actin? Oh no! ACh molecules that do not bind immediately with a receptor or those released after reacting with a receptor are hydrolyzed almost instantly (in less than 1 msec) by acetylcholinesterase. An action potential in the muscle fiber causes __________. Myosin molecules form cross-bridges when they attach to __________. Which of the following would result in muscle tension? Inside a muscle, bundles of single muscle fibers form __________. 5. The muscle action potentials that initiate contraction are transmitted from the sarcolemma into the interior of the muscle fiber by __________. Spell. Acetylcholine, transmitter substance of nerve impulses within the central and peripheral nervous systems. Which of the following produced an increase in stimulus intensity? (d) ACh binds to receptors on the postsynaptic membrane. ________________ is a ganglionic blocker of the nicotinic receptor. Aricept (or donepizil, generic) is an acetylcholinesterase inhibitor, used to treat symptoms of dementia of the Alzheimer's type. Acetylcholinesterase inhibitors (AChEIs) also often called cholinesterase inhibitors, inhibit the enzyme acetylcholinesterase from breaking down the neurotransmitter acetylcholine into choline and acetate, thereby increasing both the level and duration of action of acetylcholine in the central nervous system, autonomic ganglia and neuromuscular junctions, which are rich in acetylcholine receptors. 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