The patient dose should be measured by a suitable radioactivity calibration system immediately prior to administration. Urinary excretion is greatest in the first two days following injection. Strong oxidizer. 4 0 obj �qv$��*�=�m�V,�}�xG#Z��E�^�X�+��u�t�Cj�ذ���H��9�Y%���"_�g�}�ّ�}�����$����ڞ4�U��,�Y�D��QI���qX ����4��Ck��z��� U2.��Ik��a�3 ,����|8gj�#�Y���6��frt��/%7]udxH�S��Hk��,r���ژ؊�����R�IR��)|�7���eIZT��q��l ��(#M�����u����Q�K�\GE�UI�|9�#@EHy��`��������e�>夾�4N��-U�ø�af U��l�L�~?�Ԓd�#\_�)J��%�Ă�n���N"���ɹ�����_���c����w�׵��o���1Lmi��X�Ԍ�V�   �MFk����� t,:��.FW������8���c�1�L&���ӎ9�ƌa��X�:�� �r�bl1� Synonyms: Caution!   /Creator (Apache FOP Version 1.0) Hydrochloric …   3 0 obj Skin: The maximum range of ß- particles from Strontium-89 in tissue is approximately 8 mm. tract irritation. Chronic: Strontium chloride is a metal halide that is FDA approved for the treatment of bone pain in patients with painful skeletal metastases.     FDA-Labeled Indications and Dosage (Adult), FDA-Labeled Indications and Dosage (Pediatric), Females of Reproductive Potential and Males. d8�H�Ԛ3�iEAb1�� ��S��]�X��ȭ��ꂴR� �sr�����qgM�ԁ����[s�wĞu��\*��C��a�`8�q�CVڊ�F늑[S� �GK~�…U���o �8�Ý=��sE>�_� �!���q���mƾ"�,��*���E�AE�T���̳� �"��0Xп�����(�ar��/7�ˤ�@(L�ԡ�#��"D��୾$!B�=���J5�*>L���Z�W�n�y�^ʶ (o i+%��S��pB}A9p���"�U�#�(9D�1��9���x9{}���.C/҂��fKw5���)y@8Pބܗ�"��.ɳ� @d�2 ���X[�I�ND՛j4� ��REcm��e�o����~tF�� �<1���@��QrѢ��U]Ҕ�s��q�Ek��S,(뺸n����m1?��m��A���QBT ���� * Stability studies have shown no change in any of the product characteristics monitored during routine product quality control over the period from manufacture to expiration. Talk to your doctor about the effects of taking alcohol with this medication. AC315171000, AC315175000, S549-100, S549-500 Sub Systems, Inc.; modified using iTextSharp 4.1.6 by 1T3XT Search results for STRONTIUM CHLORIDE at Sigma-Aldrich. There is limited information regarding Overdose of Strontium chloride in the drug label. There is no FDA guidance on the use of Strontium chloride with respect to geriatric patients. *1 J�� "6DTpDQ��2(���C��"��Q��D�qp�Id�߼y�͛��~k����g�}ֺ ����LX ��X��ň��g`� l �p��B�F�|،l���� ��*�?�� ����Y"1 P������\�8=W�%�Oɘ�4M�0J�"Y�2V�s�,[|��e9�2��s��e���'�9���`���2�&c�tI�@�o�|N6 (��.�sSdl-c�(2�-�y �H�_��/X������Z.$��&\S�������M���07�#�1ؙY�r f��Yym�";�8980m-m�(�]����v�^��D���W~� ��e����mi ]�P����`/ ���u}q�|^R��,g+���\K�k)/����C_|�R����ax�8�t1C^7nfz�D����p�柇��u�$��/�ED˦L L��[���B�@�������ٹ����ЖX�! Adequate studies with Strontium-89 Chloride have not been performed to evaluate mutagenic potential or effects on fertility. material may cause a fire.   1.2. Strontium chloride MSDS Section 1: Chemical Product and Company Identification Product Name: Strontium chloride Catalog Codes: SLS4432 CAS#: 10025-70-4 RTECS: WK8400000 TSCA: TSCA 8(b) inventory: Strontium chloride CI#: Not available. Thirty-three of 40 rats injected with Strontium-89 Chloride in ten consecutive monthly doses of either 250 or 350 µCi/kg developed malignant bone tumors after a latency period of approximately 9 months. %���� Strontium-89 Chloride is excreted primarily by the, A small number of patients have reported a transient increase in. Special precautions, such as urinary catheterization, should be taken following administration to patients who are incontinent to minimize the risk of radioactive contamination of clothing, bed linen and the patient’s environment. Strontium Chloride, Granular, ACS 1.   Ingestion: %PDF-1.4 Strontium-89 Chloride Injection is not indicated for use in patients with cancer not involving bone. Mean absorbed radiation doses are listed under the Radiation Dosimetry section. Use of Strontium-89 Chloride Injection in patients with evidence of seriously compromised, In considering repeat administration of Strontium-89 Chloride Injection, the patient’s hematologic response to the initial dose, current. 10/21/2016 Strontium Chloride, Hexahydrate 2/6 NFPA Rating . AC194120000, AC194120010, AC194122500, AC315080000, AC315081000, S541-500, … Houston, Texas 77396 US Sales: 1-800-901-7247 … ;��±:Z��+���A0E�N�> << Strontium-89 is a pure beta emitter and Strontium-89 Chloride selectively irradiates sites of primary and metastatic bone involvement with minimal irradiation of soft tissues distant from the bone lesions. Catalog Numbers: /Filter /FlateDecode stream Editor-In-Chief: C. Michael Gibson, M.S., M.D. It is a typical salt, forming neutral aqueous solutions. Ingestion: 1. 6H 2 O . Company Identification: Strontium chloride is the most common form ofstrontium found in dietary supplements. Strontium Chloride Solution Flinn Scientific, Inc. P.O. Alternatively, a dose of 1.5 - 2.2 MBq/kg, 40-60 µCi/kg body weight may be used. %���� South Plainfield, NJ 07080 .     NSC721349. Urinary excretion is higher in people without bone lesions. /CreationDate (D:20110707213351-04'00') May cause eye, skin, and respiratory Radiopharmaceuticals should only be used by physicians who are qualified by training and experience in the safe use and handling of radionuclides and whose experience and training have been approved by the appropriate government agency authorized to license the use of radionuclides. <>stream MSDS Name: Strontium chloride hexahydrate Fair Lawn, NJ 07410 There is limited information regarding Postmarketing Experience of Strontium chloride in the drug label. stream There is no FDA guidance on the use of Strontium chloride with respect to specific racial populations. Strontium Chloride . �syH7P�ږZ�'�<5{x�u(�� ΚI�Tȋ�5���&'�v)����`/#gq��Q2����=���Wjo��1��,�J��+���U͕^F�+6$����r�;n6\;�U��C4�K ȥ�%pXNK���q�a�^���D�O�3&l~�l�D��;{*l����Ů���ݯ(H���8 ������\���hw,-�5� 2pV�G)ɪ��>˯m`����UL,�P����$��Ňuë�^��gc�S.G��6#s޲��3�0/��ܯ[�@� �S��FYŶ���=֝s��ݞՀ��{�g>�p�_���b��x��Ԉ<7����t���q����6�����p�Hm����)��67TT[��U,�f��-و�L6���a=H���rC��kG+�GP^s�{]������oMra�*q�/�����@nj�`�9K����1�&8��J�,�b��2��xɴ��cK�dYRI��oĶ�����Q�li�q0�מ�A�� �v~FQ��8k%�n�K8P�Q�6�W�q��J0�����o�Ǯ�B�*�ȯ.�[#�SZn��~��� (1�\a�� �*�7#(��F+ ���M�`����5��q. "���?����?����~������~���7�5��f��o���C��Q���C���_�W����?z~��������!��'�I��_C��o�k��ٯ������7�5~�_�#���v����{�������?��������*����G���������������rBO��;����G���ԟ���z�{�Y�����;��)4*9�P�i�Z��#����=?z~����!��o��0�o��{�{���ԟ�{�[���O�6��/�����G���V��~��s�7����)� ~�?�������~����������o�[��˗/�ڔ8�b�����x�r���v������o�#�/�I/�#R�ַ�����ߴ:�~��s�7 w����~��E�7����GϏ�=�?x����z�n�`�7�5���ۑcI������ߌ���o��ۿ�_���|�����?�ۿٟ��7��V[�ԻҢ��ջo�^n�;�4�o���/��W�Eя"�=?z~������=��~����7��~�r2��?�����,��������'�[����n�ַR�Է;����7���'����_� ���?����}��Qvt+����?��&���Q����GϏ���>����99�������?�`�y�?�I;��-�ߟ��_�'�N��?��������I�7-'�v/�_����5V��_5�������o��~�?i��)��;[)y����=?z~������C+>��N���N��I�7e5�#8�������N��?˪S����u�7ͷ������o�L�w~���ҟ�П��?�8�)/�{�����W݈ɏ�=?z~��������I��H�RΓփ�!��W[��j����%9�����O�@� ^�Ů�%�����ҟ�{�E�?����~3B���>��Ϛ�Y����sʙT4y�?ʈ�������Oϻw�D�j�y��ݯ�l��~������o6�������?�vb����w�KwlhO��?�G���R�ۙ�{,E��j������~�k�f��o�{���'eDoD�GϏ�=?z���P����o�n�t�W�{�����Or�����oӊ���G}��Z����E�Nҥ�~�_�|���,-ɿ�џE-���w�+��_~�� ���~����� ���9�֟�g�hQ�GϏ�=�_H�Qr�V�Iy��l���������,Y, Safety Data Sheet for Sodium Chloride (NaCl) (B1017). Skin:       4 0 obj There are no adequate and well-controlled studies in pregnant women. blood), rapid heart rate, unconsciousness and possible death. In another clinical trial, pain relief was greater in a group of patients treated with Strontium-89 compared with a group treated with non-radioactive Strontium-88. Repeated administrations of Strontium-89 Chloride should be based on an individual patient’s response to therapy, current symptoms, and hematologic status, and are generally not recommended at intervals of less than 90 days. Table 2 compares the percentage and number of patients treated with Strontium-89 Chloride Injection or placebo who had reduced pain and no increase in analgesic or radiotherapy re-treatment. May be harmful if absorbed through the skin. Emergency Phone #: Chemtrec US: 800 -424-9300 . The pH of the solution is 4 - 7.5.   Danger! 1. Strontium chloride hexahydrate is added to toothpaste to reduce pain in sensitive teeth.